What To Do If You Have Implantation Failure | Next steps After a Failed Embryo Transfer

Dr. Natalie Crawford, board-certified OB-GYN and REI, breaks down what it really means when genetically normal embryos fail to implant during IVF. She explains realistic success rates, why implantation isn’t guaranteed even with euploid embryos, and how fertility specialists evaluate recurrent implantation failure. Dr. Crawford walks through embryo factors, uterine environment, inflammation, lifestyle influences, and the different frozen embryo transfer protocols used to improve outcomes—while also addressing common tests, treatments, and misconceptions.

Questions Answered:
What can you do if normal embryos don’t implant?
What’s the difference between IVF and a frozen embryo transfer (FET)?
If the embryo is “normal,” why doesn’t it work every time?
How do your chances change after 1, 2, or 3 embryo transfers?
What is recurrent implantation failure, and how common is it?
How do egg quality, sperm quality, and cell health affect embryos?
When should you consider another IVF cycle?
What are the main types of embryo transfer cycles?
After how many failed transfers should you change the plan?
What health problems should be checked?
When should tests like saline sonogram, hysteroscopy, or ERA be used?
Should you check for chronic inflammation or infection in the uterus?
When are strong immune treatments (like IVIG) actually considered?
What lifestyle changes can lower inflammation and insulin resistance?
What blood tests can help check for insulin resistance and inflammation?
When is it a good time to get a second opinion?